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Measures of body mass such as weight and body mass index (BMI) have long been practically used as a measure for the prediction of health risks and outcomes. Although of some value, these measurements do not address an individual’ s variability in body composition (i.e. lean versus adipose tissue). Abnormalities in body composition such as low…

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Osteoporosis is a skeletal disorder characterized by loss of bone mass, reduced bone mineral density, and deterioration of bone microarchitecture, which lead to bone fragility. Bisphosphonates that are currently approved by the FDA for the prevention or treatment (or both) of osteoporosis include alendronate, ibandronate, risedronate, and zoledronic acid. This review discusses the rationale for…

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